Seminars of the Focus Area Complex Systems

Prof. Dr. C. Beta, Prof. Dr. K. Dethloff, Prof. Dr. R. Engbert, Prof. Dr. M. Holschneider, Prof. Dr. W. Huisinga, Prof. Dr. Ralf Metzler, Prof. Dr. A. Pikovsky, Prof. Dr. S. Reich, Prof. Dr. M. Rosenblum, Prof. Dr. G. Rüdiger, Prof. Dr. T. Scheffer, Prof. Dr. F. Scherbaum, Prof. Dr. J. Selbig, Prof. Dr. F. Spahn

Seminar

Speaker: Esther-Kristin Lather, MicroDiscovery GmbH and University of Potsdam

Title: Integrative Analysis of Next-Generation-Sequencing Transcriptomics and Mass Spectrometry Proteomics Data

Time: Wed, Mar 21, 2012, 10am

Place: MPI für Molekulare Pflanzenphysiologie, Room 0.21 in The Box

Abstract:
I will present a comparative analysis of transcriptomics and proteomics data derived from mouse fibroblasts (data of Schwanhäusser et al, 2011, Nature). One focus of my work is the interpretation of the transcriptomics data set (Illumina RNASeq reads). Specifically, I will compare the experimental data to simulated read data to show difficulties and ambiguities in the interpretation of the results. The second part of my presentation will be devoted to proteogenomics, the combination of RNA and protein data. I will show how evidence from transcriptomics and proteomics data can be linked on the level of reads and peptides and how the combined data can be used for the confirmation of genomic features such as splice sites.

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Past NLD Seminars (1994-2007) & (2008 ...)

Students' seminar: Theoretical Physics, PIK, Modeling & TSA Berlin-Potsdam-Colloquia: PhysGesellschaft Berlin, TU Berlin, Pro Physik, AIP, AEI, MPI-KGF, GFZ, HMI, PIK, AWI, Max Planck Institute for the History of Science, Mathematik, DPG Disputationen, & Vorschau UP

Udo Schwarz, Zentrum für Dynamik komplexer Systeme,
Universität Potsdam, Campus Golm Karl-Liebknecht-Str. 24, 14476 Potsdam, building 28, room 2.107
Phone: (+49-331) 977-1658, Fax : (+49-331) 977-1045

Email: Udo.Schwarz AT uni-potsdam.de

DFG SFB 1294

DFG Sonderforschungsbereich 1294 Data assimilation

DFG SPP 1488

DFG Schwerpunktprogramm 1488 Planetmag


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