Seminars of the Focus Area Complex Systems

Prof. Dr. C. Beta, Prof. Dr. K. Dethloff, Prof. Dr. R. Engbert, Prof. Dr. M. Holschneider, Prof. Dr. W. Huisinga, Prof. Dr. Ralf Metzler, Prof. Dr. A. Pikovsky, Prof. Dr. S. Reich, Prof. Dr. M. Rosenblum, Prof. Dr. G. Rüdiger, Prof. Dr. T. Scheffer, Prof. Dr. F. Scherbaum, Prof. Dr. J. Selbig, Prof. Dr. F. Spahn

Seminar

Speaker: Philippe Robert, INRIA, Paris, France

Title: Stochastic Models of Gene Expression * SFB 1294 colloquium

Time: Fri, Oct 13, 2017, 10:15am

Place: bldg 28, room 0.108

Abstract:
Protein production is a key process of prokaryotic and eukaryotic cells consuming more that 80% of their resources. The cytoplasm of the cell being a disorganized medium subject to thermal noise, the protein production process has an important stochastic component. In this context the random fluctuations of the number of copies of a given protein in a cell are of primary importance. We discuss the impact of modelling issues of this production process through the use of Markovian and nonMarkovian models. Mathematical models of the production of one fixed type of proteins is presented. When several classes of proteins are considered, an important additional aspect has to be taken into account, the limited common resources of the cell (polymerases and ribosomes) used by the production process. A large scale analysis is proposed in this setting. We conclude by an analysis of the impact of some feedback mechanisms to control the fluctuations of the number of proteins.

Joint Work with Renaud Dessalles, Vincent Fromion and Emanuele Leoncini.

Back to the seminar schedule



Past NLD Seminars (1994-2007) & (2008 ...)

Students' seminar: Theoretical Physics, PIK, Modeling & TSA Berlin-Potsdam-Colloquia: PhysGesellschaft Berlin, TU Berlin, Pro Physik, AIP, AEI, MPI-KGF, GFZ, HMI, PIK, AWI, Max Planck Institute for the History of Science, Mathematik, DPG Disputationen, & Vorschau UP

Udo Schwarz, Zentrum für Dynamik komplexer Systeme,
Universität Potsdam, Campus Golm Karl-Liebknecht-Str. 24, 14476 Potsdam, building 28, room 2.107
Phone: (+49-331) 977-1658, Fax : (+49-331) 977-1045

Email: Udo.Schwarz AT uni-potsdam.de

DFG SFB 1294

DFG Sonderforschungsbereich 1294 Data assimilation

DFG SPP 1488

DFG Schwerpunktprogramm 1488 Planetmag


News: odeint C++ library

Check out boost::odeint – our fast and flexible C++ library for integrating differential equations!