Seminars of the Focus Area Complex Systems

Prof. Dr. C. Beta, Prof. Dr. K. Dethloff, Prof. Dr. R. Engbert, Prof. Dr. M. Holschneider, Prof. Dr. W. Huisinga, Prof. Dr. Ralf Metzler, Prof. Dr. A. Pikovsky, Prof. Dr. S. Reich, Prof. Dr. M. Rosenblum, Prof. Dr. G. Rüdiger, Prof. Dr. T. Scheffer, Prof. Dr. F. Scherbaum, Prof. Dr. J. Selbig, Prof. Dr. F. Spahn

Seminar

Speaker: Sabrina Donner, PIK and HU Berlin

Title: Inferring regulatory networks from short time series

Time: Thu, Mar 17, 2011, 3pm

Place: bldg 14, room 3.02/03

Abstract:
Many systems of interest can be regarded as complex networks of multiple interacting subsystems. Due to the partial available knowledge about the underlying network topology and dynamics, the analysis of empirical multivariate time-resolved data is crucial to understand the drive-response relationships and to reconstruct these networks. However, in many cases, particularly in biology, the time series are rather short. Thus, many standard association measures do not resolve the coupling issue. We introduce here the "inner composition alignment" (IOTA), a novel permutation-based asymmetric association measure, and show that under well defined conditions, IOTA can infer the direction of coupling, detect superfluous links and account for autoregulation. Additionally, we compare the performance of IOTA to that of common correlation measures, in particular Kendall's rank correlation.

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Past NLD Seminars (1994-2007) & (2008 ...)

Students' seminar: Theoretical Physics, PIK, Modeling & TSA Berlin-Potsdam-Colloquia: PhysGesellschaft Berlin, TU Berlin, Pro Physik, AIP, AEI, MPI-KGF, GFZ, HMI, PIK, AWI, Max Planck Institute for the History of Science, Mathematik, DPG Disputationen, & Vorschau UP

Udo Schwarz, Zentrum für Dynamik komplexer Systeme,
Universität Potsdam, Campus Golm Karl-Liebknecht-Str. 24, 14476 Potsdam, building 28, room 2.107
Phone: (+49-331) 977-1658, Fax : (+49-331) 977-1045

Email: Udo.Schwarz AT uni-potsdam.de

DFG SFB 1294

DFG Sonderforschungsbereich 1294 Data assimilation

DFG SPP 1488

DFG Schwerpunktprogramm 1488 Planetmag


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